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The comparisons between zyban, nts, and combination treatment in this trial have not been replicated, and, therefore should not be interpreted as demonstrating the superiority of any of the active treatment arms over any other.

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For the findings of LVOTO and VSD.the studies were limited by the small number of exposed cases.inconsistent findings among studies.and the potential for chance findings from multiple comparisons in case control studies.

Adverse reactions in a 1-year maintenance trial and a 12-week COPD trial with ZYBAN were quantitatively and qualitatively similar to those observed in the dose-response and comparator trials.

There are reports of arthralgia.myalgia.fever with rash and other serum sickness-like symptoms suggestive of delayed hypersensitivity.

Instruct patients to discontinue ZYBAN and not restart it if they experience a seizure while on treatment. Advise patients that the excessive use or abrupt discontinuation of alcohol.benzodiazepines.antiepileptic drugs.or sedatives/hypnotics can increase the risk of seizure. Advise patients to minimize or avoid use of alcohol.

Many drugs can interact with bupropion. Tell your zyban cheap about all medicines you use.and those you start or stop using during your treatment with Zyban. This includes prescription and over-the-counter medicines.vitamins.and herbal products. Not all possible interactions are listed in this medication guide.

Advise patients regarding the following issues and to alert their prescriber if these occur while taking ZYBAN.

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