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XELODA dosage may need to be individualized to optimize patient managementPatients should be carefully monitored for toxicity and doses of XELODA should be modified as necessary to accommodate individual patient tolerance to treatmentsee Clinical StudiesToxicity due to XELODA administration may be managed by symptomatic treatmentdose interruptions and adjustment of XELODA doseOnce the dose has been reducedit should not be increased at a later timeDoses of XELODA omitted for toxicity are not replaced or restoredinstead the patient should resume the planned treatment cycles.

There was no improvement in one-year progression-free survival rate and one-year overall survival rate in pediatric patients with newly diagnosed intrinsic brainstem gliomas who received capecitabine relative to a similar population of pediatric patients who participated in other clinical trials.

NoteBreast Cancer News is strictly a news and information website about the diseaseIt does not provide medical advicediagnosis or treatmentThis content is not intended to be a substitute for professional medical advicediagnosisor treatmentAlways seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical conditionNever disregard professional medical advice or delay in seeking it because of something you have read on this website.

Patients receiving concomitant capecitabine and oral coumarin-derivative anticoagulant therapy should have their anticoagulant responseINR or prothrombin timemonitored closely with great frequency and the anticoagulant dose should be adjusted accordinglysee BOX WARNING and DRUG INTERACTIONS

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