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As a reason for the company s behaviour, it is alleged that the german public healthcare system spends an additional 99 million per annum on nexium as compared to using omeprazole, which however would be less profitable for the company as its patent protection has expired.

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the effect of nexium on serum gastrin concentrations was evaluated in approximately 2,700 patients in clinical trials up to 8 weeks and in over 1,300 patients for up to 6 to 12 months.

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