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Exclusion criteria were pregnancy, fever, signs of meningismus, altered sensorium, drug or alcohol use, oxygen saturation less than 90 , recent trauma or seizure, worst headache, abnormal blood pressure, recent within 48 hours use of metoclopramide or prochlorperazine, and allergy to metoclopramide or prochlorperazine.

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in many respects, this medication can be useful as an acetylcholine release-promoter similar to gastrointestinal drugs such as metoclopramide and cisapride.

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increased plasma concentrations of metoclopramide; risk of exacerbation of extrapyramidal symptoms see clinical pharmacology 12.

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