Digoxin increases the force of contraction of the muscle of the heart by inhibiting the activity of an enzyme atpase that controls movement of calcium, sodium and potassium into heart muscle.
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thus, the dosage of digoxin should be carefully selected and monitored in elderly patients see use in specific populations 8.
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in the newborn period, renal clearance of digoxin-zori is diminished and suitable dosage adjustments must be observed.
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race differences in digoxin-zori pharmacokinetics have not been formally studied.
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digoxin is prescribed to treat heart failure, a long-term, chronic condition.
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no special preparation is needed, but timing of sample collection is important and you may be instructed to have your blood drawn a specific number of hours after your last dose of digoxin.
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