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because of the current uncertainty regarding the dose-response relationship between chloramphenicol ingestion and aplastic anemia, it is not possible to define a safe level for the presence of this antibiotic in food products.

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however, in keeping with the current recommendations and warnings for use, prescribers are reminded that topical chloramphenicol should be reserved for use only in infections for which it is indicated and only where a family history of drug-related haemopoietic toxicity has been excluded.


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